Bilateral Idiopathic Multifocal Retinal Pigment Epithelial Detachments: A Case Report and Brief Review of the Literature

Published Date: 15th June 2025

Publication Authors: Kalogeropoulos. D, Ibraheem. A, Dragnev. D

Retinal pigment epithelial detachments (PEDs) result from a disruption at the junction between the basement membrane of the retinal pigment epithelium (RPE) and the innermost part of Bruch's membrane. Serous retinal PEDs, whether singular or multiple, are frequently seen across a broad spectrum of ophthalmic disorders. Additionally, PEDs have been associated with various systemic conditions, including renal, hypertensive, endocrine, and hematologic disorders. Idiopathic PEDs, which occur without an associated underlying condition, are exceedingly rare, with only a few cases reported in the literature. Herein, we report a case of an asymptomatic and otherwise healthy individual with multiple idiopathic retinal PEDs, highlighting the importance of a comprehensive clinical examination and multimodal ophthalmic imaging.

Kalogeropoulos, D.; Ibraheem, A.; Dragnev, D. (2025). Bilateral Idiopathic Multifocal Retinal Pigment Epithelial Detachments: A Case Report and Brief Review of the Literature. Cureus. 17(6), p.e86048. [Online]. Available at: https://www.cureus.com/articles/377688-bilateral-idiopathic-multifocal-retinal-pigment-epithelial-de [Accessed 23 July 2025].

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