Sandwich Technique: A Technique to Increase Diagnostic Yield of Bone Biopsy

Published Date: 01st April 2025

Publication Authors: Iyengar. KP

Objective: 
To describe a novel, simple technique to increase the diagnostic accuracy of computed tomography (CT) guided bone biopsy. This is to ensure the adequacy of the histopathological specimen and avoid suboptimal samples.

Materials and Methods: 
The sandwich technique (ST) involves retaining the pathological sample between two slabs of normal bone tissue by passing the bone biopsy needle further past the abnormal area within the bone.

Results: 
We have used this technique for successful bone biopsy samples of musculoskeletal lesions in a tertiary orthopedic oncology center in over 61 cases with near 100% diagnostic rate.

Conclusion: 
The ST is a simple, yet effective and inexpensive reproducible technique to increase diagnostic accuracy of histopathological specimens in bone lesions.

Shah, A.; Iyengar, K.P. et al. (2025). Sandwich Technique: A Technique to Increase Diagnostic Yield of Bone Biopsy. Journal of Arthroscopy and Joint Surgery. 12(2), pp.93-96. [Online]. Available at: https://journals.lww.com/jajs/fulltext/2025/04000/sandwich_technique__a_technique_to_increase.6.aspx [Accessed 23 July 2025].

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