Publications

Development of guidance for initiation and deprescribing PPI

Published Date: 05th December 2022

Publication Authors: Thein M


Abstract
It is important to consider whether the risks outweigh the benefits in long term proton pump inhibitor as there has been increasing use of PPIs in hospital settings and community especially in elderly care. Data collection was done on the patients admitted to care of elderly wards in Whiston hospital from February to April 2022. 51% of patients were prescribed with PPIs, majority more than 80% of the PPI prescriptions were originated in community. The indication of PPI due to concomitant medications such as antiplatelets, anticoagulants, steroids and NSAIDs is more common than having dyspepsia and GERD related symptoms alone. On the other hand, half of the inpatients receiving above medications are also not prescribed with PPIs, which indicates the controversy on initiation of PPIs on patients with potential ulcerative medications. Moreover, 10% of the patients with PPI prescription from community without evidence of indication were discharged with the continuing prescription. Therefore, in order to in order to optimise safety and avoid unnecessary prescription, the guidance for initiation and deprescribing PPI is developed to apply in St Helens and Knowsley hospital trust.

 

Thein, M. (2022). Development of guidance for initiation and deprescribing PPI. European Geriatric Medicine. 13(Suppl 1), pp.S408-S409. [Online]. Available at: https://doi.org/10.1007/s41999-022-00711-8 [Accessed 21 February 2023]

 

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