Research Development
Staff Publications
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Staff Publications
Research Development
Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.
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Background This study assessed the potential cost-effectiveness of high (80–100%) vs low (21–35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. Methods Decision-analytic models were constructed using best available evidence sourced from unbundled data of an ongoing pilot trial assessing..
Published: | 13/09/2023 |
Authors: | Kaul A |
Introduction Giant cell arteritis (GCA), a medium-to-large-vessel vasculitis affecting the over-50s, is a rare cause of ischaemic stroke, favouring the vertebrobasilar circulation. Erythrocyte sedimentation rate (ESR) is often used to help exclude the diagnosis but this is not always reliable. We discuss a case of ischaemic stroke due to..
Published: | 17/01/2023 |
Authors: | Kaul A, Seed A, Cooney L |
Background Laparoscopic cholecystectomy is one of the most frequently performed operations in the United Kingdom, commonly due to symptomatic gallstones. Delay between diagnosis and definitive surgical intervention often leads to a significant readmission rate, growing financial burden and increased complexity of the ultimate surgical intervention. Resource reallocation and reduced operational..
Published: | 14/06/2021 |
Authors: | Clifford R, Rajput K, Naing CY, MacDonald K, Pantak T, Kaul A |
Background Over 16,000 cases of oesophago-gastric cancer are diagnosed in the UK annually. Multi-modality staging of these cancers include computer tomography, endoscopic ultrasound and positron emission topography. Laparoscopy and peritoneal lavage are recommended as an additional staging modality due to the propensity of these cancers to rapidly metastasise to lymph nodes..
Published: | 01/11/2019 |
Authors: | Kaul A |
Abstract Background Barrett's oesophagus is a precursor to the development of oesophageal adenocarcinoma. This study sought to clarify the role of genetic, chromosomal and proliferation biomarkers that have been the subjects of multiple studies through meta-analysis. Methods MEDLINE, Embase, PubMed and the Cochrane Library were searched for clinical studies assessing..
Published: | 28/04/2017 |
Authors: | Altaf K, Hickey L, Kaul A |
Abstract Background Barrett’s Oesophagus (BO) is a precursor for Oesophageal Adenocarcinoma (OAC). Currently, there are no biomarkers in clinical practice that predict the malignant progression in BO. We sought to clarify the effectiveness of common genetic aberrations as potential biomarkers through a systematic review and meta-analyses. Methods MEDLINE, EMBASE..
Published: | 17/02/2017 |
Authors: | Altaf K, Hickey L, Kaul A |
Background The base of appendix can be secured by stapling or with endoloops. The authors have reported the use of Johan forceps as endoloop pushers for laparoscopic appendicectomy. Objectives A feasibility study of safety and cost effectiveness of using Johan forceps as endoloop pushers for laparoscopic appendicectomy. Material and Methods..
Published: | 19/07/2016 |
Authors: | Kaul A |
Siddique, K; Holmes, J; Kaul, A. (2013). Lean initiative to develop managed clinical network to improve outcomes for upper GI cancer patients in Saint Helens & Knowsley . European Journal of Cancer,. 49 (Suppl 2), S592
Published: | 19/07/2016 |
Authors: | Holmes J, Kaul A |
Aims: Laparoscopic cholecystectomy has been widely accepted as a day case procedure but many trusts struggle to attain this. Techniques have been described to reduce pain and immediate/early complications from surgical and anaesthetic perspectives. We evaluated our theatre practices, targeting areas of improvement, to create and implement a "Proactive..
Published: | 19/07/2016 |
Authors: | Mann K, Graham M, Purlackee S, Ray A, Kaul A, Kuduvalli P |
Introduction Current investigation for patients with colorectal symptoms without overt rectal bleeding is undertaken by colonoscopy or by flexible sigmoidoscopy and barium enema. A large majority of patients do not have colorectal cancer. There exists no instant, objective measure to discriminate patients who are likely to have colorectal cancer and..
Published: | 19/07/2016 |
Authors: | Kaul A |
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