Research Development

Staff Publications

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Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Bassi A'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

Opioid use and associated factors in 1676 patients with inflammatory bowel disease: a multicentre quality improvement project

Objective Despite its association with poorer outcomes, opioid use in inflammatory bowel disease (IBD) is not well characterised in the UK. We aimed to examine the extent of opioid use, the associated factors and the use of mitigation techniques such as pain-service review and opioid weaning plans among individuals with..

Published: 14/06/2023
Authors: Bassi A

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P0490 Opioid exposure in IBD and associated factors: a UK prospective multicentre audit of 1362 patients

Introduction Opioid exposure in inflammatory bowel disease (IBD) is associated with premature mortality, yet exposure in IBD increasing. International guidelines have been introduced to rationalise opioid use. While opioids may improve acute pain, long term exposure is rarely beneficial and is associated with side effects.We conducted a multicentre audit..

Published: 09/10/2022
Authors: Bassi A

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PTU-84 Accelerated accreditation for bowel cancer screening colonoscopist in cheshire and merseyside

Introduction In 2020, as the COVID pandemic spread through the UK, Bowel Cancer screening invitations were paused. In Cheshire and Merseyside (C & M) there were as many as 100,000 patients waiting for their invitations. In addition, there were a large number of patients who had already been tested but waiting for colonoscopy..

Published: 07/11/2021
Authors: Bassi A

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PO557 Faecal immunochemical test (FIT) in secondary care: Prioritising lower GI two week wait patients during the COVID-19 pandemic

Introduction FIT provides a safe, rapid and accurate way to determine a patient’s risk of having a lower GI cancer and it may possibly be used to exclude cancer for patients with negative result. It will reduce primary care referrals by enabling GPs to determine likelihood of lower GI..

Published: 11/10/2021
Authors: Bassi A

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Assessment of steroid use as a key performance indicator in inflammatory bowel disease

Background Patients with inflammatory bowel disease (IBD) are at risk of excess corticosteroids. Aims To assess steroid excess in a large IBD cohort and test associations with quality improvement and prescribing. Methods Steroid exposure was recorded for outpatients attending 19 centres and associated factors analysed. Measures taken to avoid excess were..

Published: 23/12/2019
Authors: Bassi A

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P576 Impact of improved access to biologic therapies and physician engagement on excess steroid exposure: Results from a UK audit of 3561 patients

Background Steroid-free remission is an important goal of IBD therapy. Improved access to effective therapies and changes in physician awareness of excess steroid exposure might impact this goal. The aim of this study was to evaluate temporal changes in steroid prescribing in UK IBD outpatients in the context of major..

Published: 09/04/2018
Authors: Bassi A

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A multi-centre audit of excess steroid use in 1176 patients with inflammatory bowel disease

​BACKGROUND: Corticosteroids are central to inducing remission in inflammatory bowel disease (IBD) but are ineffective maintenance agents. AIM: To benchmark steroid usage in British outpatients and assess factors associated with excess exposure. METHODS: We recorded steroid use in unselected IBD outpatients. Cases meeting criteria for steroid dependency or excess were..

Published: 03/01/2018
Authors: Bassi A

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Excess steroid use in IBD

Background Corticosteroids are the cornerstone of induction of remission in active IBD but are limited in their ability to maintain remission, and are associated with significant side effects. ECCO defines appropriate steroid use and recommends an exit strategy for steroid dependent patients. Data to support the utility of clinical and..

Published: 21/02/2017
Authors: Bassi A

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PWE-374 Is ct colonoscopy ready for prime time as first line investigation for high risk patients?

​ Introduction   With CT virtual colonoscopy (CTVC) emerging as a widely available sensitive tool in the investigation of GI pathology, we changed our practice, and are now investigating patients presenting in our “one stop – 2 week rule” gastroenterology clinic with lower GI symptoms with a flexible sigmoidoscopy followed by a CTVC on..

Published: 19/07/2016
Authors: Bennett B, Bassi A

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A Model To Assess The Cost Of Flare In Ulcerative Colitis (UC)

​ Introduction  Disease flare in ulcerative colitis (UC) can result in substantial cost implications to the NHS. While the costs associated with treatment and management of UC are well-documented, estimates of the cost of flare are lacking. A cost analysis was performed to construct a model to estimate the costs associated..

Published: 19/07/2016
Authors: Bassi A

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The IBD-control questionnaire

​ Introduction  Routine capture of reliable, patient-centred health status measures for IBD has not become part of standard practice. The IBD-Control questionnaire is a short (13 item), generic patient-reported outcome measure which we developed to support routine care.1 Methods  To further define performance in varied settings, we undertook: (A) A prospective study..

Published: 19/07/2016
Authors: Collins B, Bassi A

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Nurse led one stop upper GI clinics are safe and allow rapid assessment of patients

​ Introduction  Meeting 2 week referral targets presents a challenge to many hospitals. Commonly patients are seen in clinic prior to investigation with resultant additional delays in time to investigation. Nurse led one stop clinics where patients undergo clinical assessment and endoscopic and/or radiological assessment on the same day have the..

Published: 19/07/2016
Authors: Williams S, Ashall B, Cave G, Bassi A

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Clinic Outcomes For Unselected Patients

​ Introduction  There is a well-established role of specialist nurses in on-going management of chronic diseases in specialist clinics. With the reduction in junior doctor hours, advanced nurse clinicians (ANC) are taking on increasing complex medical roles. We aimed to evaluate the effectiveness of ANC in managing unselected new patients (NP)..

Published: 19/07/2016
Authors: McClements D, McLindon J, Chandy R, Priestley S, Fox M, Theis V, Dobson J, Bassi A

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Delivery of Parenteral Nutrition

​ Introduction  Recent report by NCEPOD into hospital care of patients receiving parenteral nutrition (PN) suggested that only 19% adult patients had PN care that was considered to represent good practise. An initial audit (retrospective audit over six months) in our hospital suggested lack of quality control at the point of initiation..

Published: 19/07/2016
Authors: Whittingham C, Bassi A

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Secondary care costs in oesophagogastric cancer

​ Introduction  Published data describing the scale, profile and determinants of healthcare resource use for oesophago-gastric cancer (OGC) are scarce, particularly for the UK. The National Cancer Plan (2000) encouraged greater use of imaging for staging and increased use of oncological therapies but the major modalities of palliation and curative surgery have..

Published: 19/07/2016
Authors: Bassi A

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