Research Development

Staff Publications

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Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Jois RHS'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

Feasibility of breast lesion localisation using Sirius Pintuition

Introduction Impalpable breast cancers can be localised using different techniques. Recently, magnetic seed localisation systems have been developed and shown to offer benefits over traditional wire guided techniques. This study aims to assess the feasibility of a new seed localisation device, Sirius Pintuition, at St Helen's and Knowsley NHS Trust.  ..

Published: 02/05/2022
Authors: Foster R, Bathla S, Harris O, Jois RHS, Kiernan T, Ray A, Chagla LS

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P179. Comparing roll and magseed in management of impalpable breast lesions a single unit experience

Background Screening and the use of Neoadjuvant therapy has increased the number of breast lesions requiring localisation. The search for the ideal technique is still on. ROLL (Radioisotope guided Occult Lesion Localisation) is a reliable technique though not widely available, Magnetic Seed, is a new alternative. These two techniques have..

Published: 01/05/2021
Authors: Jois RHS, Pushdary KH, Patnam V, Gupta N, Kiernan T, Bathla S, Ray A, Harris O, Chagla LS

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Re-excision After Breast Conservation Surgery – Our Breast Unit experience

Background The benefit of re-excision surgery for involved margin after BCS among the patient receiving adjuvant radiotherapy is unclear. Omission of re-excision surgery for selected patients with focally involved margin after BCS did not alter DFS and OS. Knowing the biology of cancer may assist to select patients benefiting with..

Published: 23/12/2019
Authors: Pushdary KH, Atherton J, Ray A, Jois RHS

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Simple reconstructive techniques for conservative breast cancer surgery

Background Patients undergoing breast conservation surgery (BCS) for cancer may benefit with the defect reconstruction using simple techniques to obtain optimal cosmetic & oncological outcome. Aim To determine feasibility simple oncoplastic level 2 reconstruction as a day case. Material and Methods A prospective series of patients eligible for BCS & likely to have..

Published: 25/04/2017
Authors: Jois RHS,

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Localization techniques for guided surgical excision of non-palpable breast lesions

​ Background Breast cancer is the most common form of cancer and the second leading cause of death amongst women in Europe. Amongst five invasive cancers per 1000 women detected in screening, 2.7 were < 15 mm in diameter; and others reported that over one third of excised breast lesions were clinically occult. The challenge..

Published: 19/07/2016
Authors: Jois RHS,

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ROLL after neo adjuvant treatment

​ Neo-adjuvant chemo & hormone therapy is very effective in reducing the size of the primary breast cancer: this may result into a substantial response, hence the need to localise a non-palpable lesion. A variety of localisation techniques are used to target surgical removal of these subclinical lesions i.e., Wire marker,..

Published: 19/07/2016
Authors: Jois RHS, Harris O,

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Breast cancer recurrence after ROLL lumpectomy

​ Background Very few literatures are available on the long term outcomes after Radioguided Occult Lesion Localisation (ROLL) guided lumpectomy for non palpable invasive breast cancer. We previously published a recurrence of 1.9% with median follow up of 33 months. This is the first observation reporting after a Ten year experience with ROLL...

Published: 19/07/2016
Authors: Jois RHS, Carini S, Harris O, Thind R, Desmond S, Ray A, Chagla LS, Bulgasim N,

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Pathologic Response of Breast Cancer

​ Background:  Neo-adjuvant chemotherapy is being increasingly used for breast cancer. MRI is used for assessing tumour response. Literature on correlation of pathologic response and MRI response is scanty. Aim:  Can a pre-operative MRI predict pathologic response of breast cancer to neo-adjuvant chemotherapy? Methods:  A consecutive series of patients with invasive..

Published: 19/07/2016
Authors: , Jois RHS, Harris O, Pennick M

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ROLL failure rates

​ Background:  We have used Radioisotope Occult Lesion Localization (ROLL) of breast lesions at our unit since 2002. Literature reports failure rates of 4 - 10% for Wire Guided Localisation (WGL). Ours is the first reporting of the difficulties with ROLL (UK) and lessons learnt from it. Method:  A consecutive series of patients underwent..

Published: 19/07/2016
Authors: , Carini S, Harris O, Thind R, Desmond S, Jois RHS

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Impalpable Breast Cancer

​ Background:  The detection of impalpable breast cancer lesions is on the rise due to mass population screening. Radio-guided occult lesion localisation (ROLL) has recently been used in the management of early lesions while sentinel lymph node biopsy (SLNB) has been used to detect occult lymph node metastases. In order to..

Published: 19/07/2016
Authors: Herbert J, , Chagla LS, Desmond S, Galea M, Harris O, Ray A, Thind R, Jois RHS

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Sentinel lymph node biopsy

​ Background:  Sentinel lymph node biopsy (SLNB) is an established method of assessing axillary node status in women with early breast cancer. The primary aim of SLNB is to understand lymph node status with minimal morbidity. Current practice is to offer completion axillary clearance for those women with metastases in sentinel..

Published: 19/07/2016
Authors: Galea M, Jois RHS, Swaminathan V, Chagla LS, Thind R, Harris O, Desmond S,

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Secondary Breast Cancers

​ Background:  Occurrence of metastatic disease to breast (secondary breast cancer) in both women and men is rare, constituting 0.5-6% of breast malignancy. In addition to systematic history taking and clinical examination, early diagnosis of secondary breast cancer demands vigilance by radiologists to distinguish subtle disparities between much commoner primary breast..

Published: 19/07/2016
Authors: Kulkarni T, , Jois RHS, Harris O, Thind R

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ROLL Lumpectomy

​Background  Occult breast lesions are being successfully targeted by means of Radioactive-guided Occult Lesion Localization (ROLL). Several reports demonstrate suitability of ROLL technique to excise non-palpable breast lesions with immediate advantages. Aim  Evaluation of long-term outcomes after ROLL guided lumpectomy for early breast cancer. Materials and methods  A consecutive series..

Published: 19/07/2016
Authors: , Chagla LS, Desmond S, Harris O, Poonawala S, Thind R, Jois RHS

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Prediction of Non Sentinel Nodal Metastases After Positive Sentinel Lymph Node Biopsy for Early Breast Cancer – Burney Breast Unit Experience

Background: Sentinel lymph node biopsy (SLNB) is an established method of assessing axillary node status in women with early breast cancer. The primary aim of SLNB is to understand lymph node status with minimal morbidity. Current practice is to offer completion axillary clearance for those women with metastases in sentinel..

Published: 19/07/2016
Authors: Galea M, Jois RHS, Swaminathan V, Chagla LS, Thind R, Harris O, Desmond S,

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St Helens Community Staff

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Knowsley Community Staff

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Halton Community Staff

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North West Boroughs Community Health Staff

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