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ST HELENS AND KNOWSLEY HOSPITAL STAFF - PUBLICATIONS PRE APRIL 2024
- Aabideen K
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- ST HELENS COMMUNITY STAFF
Staff Publications
Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.
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All publications by 'McLindon J'
Mersey and West Lancashire Teaching Hospitals Staff
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St Helens and Knowsley Hospital Staff - Publications pre April 2024
X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis
Background & Aims Genome-wide association studies in primary biliary cholangitis (PBC) have failed tofind X chromosome (chrX) variants associated with the disease. Here, we specificallyexplore the chrX contribution to PBC, a sexually dimorphic complex autoimmune disease. Methods We performed a chrX-wide association study, including genotype data from 5 genome-wideassociation studies (from Italy,..
| Published: | 01/06/2021 |
| Authors: | McLindon J |
The UK-PBC risk scores: Derivation and validation of a scoring system for long-term prediction of end-stage liver disease in primary biliary cholangitis
Abstract The biochemical response to ursodeoxycholic acid (UDCA)—so-called “treatment response”—strongly predicts long-term outcome in primary biliary cholangitis (PBC). Several long-term prognostic models based solely on the treatment response have been developed that are widely used to risk stratify PBC patients and guide their management. However, they do not..
| Published: | 26/10/2016 |
| Authors: | McLindon J |
International genome-wide meta-analysis
Abstract Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We..
| Published: | 19/07/2016 |
| Authors: | McLindon J |
Clinic Outcomes For Unselected Patients
Introduction There is a well-established role of specialist nurses in on-going management of chronic diseases in specialist clinics. With the reduction in junior doctor hours, advanced nurse clinicians (ANC) are taking on increasing complex medical roles. We aimed to evaluate the effectiveness of ANC in managing unselected new patients (NP)..
| Published: | 19/07/2016 |
| Authors: | McClements D, McLindon J, Chandy R, Priestley S, Fox M, Theis V, Dobson J, Bassi A |
St Helens Community Staff
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Knowsley Community Staff
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Halton Community Staff
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North West Boroughs Community Health Staff
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