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ST HELENS AND KNOWSLEY HOSPITAL STAFF - PUBLICATIONS PRE APRIL 2024
- Aabideen K
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- Simpson GS
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- ST HELENS COMMUNITY STAFF
Staff Publications
Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.
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All publications by 'Nicholson T'
Mersey and West Lancashire Teaching Hospitals Staff
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St Helens and Knowsley Hospital Staff - Publications pre April 2024
Ibrutinib as first line therapy for mantle cell lymphoma: A multicentre, real-world UK study
Abstract During the Covid-19 pandemic, ibrutinib +/- rituximab was approved in England for initial treatment of mantle cell lymphoma (MCL) instead of immunochemotherapy. As limited data are available in this setting, we conducted an observational cohort study evaluating safety and efficacy. Adults receiving ibrutinib +/- rituximab for untreated MCL were..
| Published: | 21/12/2023 |
| Authors: | Nicholson T |
P1141: Ibrutinib and rituximab as first line therapy for mantle cell lymphoma: a multicentre, real-world UK study
Background Ibrutinib (IBR) is an oral covalent Bruton tyrosine kinase inhibitor (BTKi), licensed for treatment of relapsed or refractory mantle cell lymphoma (MCL). Under NHS interim Covid-19 agreements in England, IBR with or without rituximab (R) was approved for the frontline treatment for MCL patients (pts) as a safer alternative..
| Published: | 14/06/2022 |
| Authors: | Nicholson T |
A retrospective observational study to evaluate the clinical outcomes and routine management of patients with chronic lymphocytic leukaemia...
Summary Idelalisib (IDL) is an oral first-in-class phosphatidylinositol 3-kinase delta (PI3Kδ) inhibitor approved for chronic lymphocytic leukaemia (CLL) alongside rituximab (R) since 2014. However, little data exist on routine practice. The RETRO-idel was a protocol-led, retrospective study of 110 patients [n = 27 front-line (1L)] who received IDL-R. The primary end-point was clinical..
| Published: | 08/07/2021 |
| Authors: | Nicholson T |
Second primary malignancies in patients receiving treatment with ruxolitinib for myelofibrosis – a regional experience
Patients with myeloproliferative neoplasms (MPN) are at an increased risk of second primary malignancies (SPM) compared with matched‐controls and the general population. The Surveillance, Epidemiology and End Results (SEER) database (US cancer registries) reported that patients with primary myelofibrosis (PMF) had an incidence of SPM of 5·3% after a median..
| Published: | 01/05/2020 |
| Authors: | Nicholson T |
A unique presentation of destructive shoulder arthropathy in the chronic phase of chronic myeloid leukaemia
We present a previously unreported case of rapidly progressing, destructive shoulder arthropathy as an initial presentation of chronic phase chronic myeloid leukaemia. This patient initially presented to clinic for consideration of an arthroplasty for symptom relief; however, her loss to follow-up yielded a rapid progression of her symptoms. Bone marrow..
| Published: | 26/06/2019 |
| Authors: | Connolly S, Howard J, MacKenzie B, Nicholson T, |
Haematology Speciality Trainees Driving NIHR Clinical Research
Abstract In 2016, the NIHR Haematology National Speciality Group founded a pilot programme to develop the clinical research skills of Haematology trainees within Non‐Malignant Haematology (NMH). This unique initiative has since been rolled out successfully throughout CRNs nationwide and equips Haematology trainees with the skills to become future leaders in..
| Published: | 05/06/2018 |
| Authors: | Loizou E, Nicholson T |
Genotype-guided dosing of warfarin
BACKGROUND The level of anticoagulation in response to a fixed-dose regimen of warfarin is difficult to predict during the initiation of therapy. We prospectively compared the effect of genotype-guided dosing with that of standard dosing on anticoagulation control in patients starting warfarin therapy. METHODS We conducted a multicenter, randomized, controlled..
| Published: | 19/07/2016 |
| Authors: | Nicholson T |
St Helens Community Staff
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Knowsley Community Staff
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Halton Community Staff
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North West Boroughs Community Health Staff
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