Research Development

Staff Publications

 Small purple icon of a book with a magnifying glass on top  Staff Publications

Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Clewes A'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

A panel of urinary proteins predicts active lupus nephritis and response to rituximab treatment

Objectives ∼30% of patients with SLE develop LN. Presence and/or severity of LN are currently assessed by renal biopsy, but biomarkers in serum or urine samples may provide an avenue for non-invasive routine testing. We aimed to validate a urinary protein panel for its ability to predict active renal involvement..

Published: 12/12/2020
Authors: Dawson J, McCaffrey P, Graham D, Williams E, Clewes A, Hornby N

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FRAX analysis

​ Background  Bone health is a significant problem with over 300,000 patients presenting with fragility fractures to hospitals in the UK each year resulting in 20% mortality and 50% disability. FRAX and Q fracture are two fracture risk-assessment tools available to use in the UK. FRAX is an important tool to assess 10-year fracture..

Published: 19/07/2016
Authors: Tayal V, Abernethy R, Clewes A, Dawson J, O'Rourke T

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Assessing the cardiovascular risk burden

​ Background  Rheumatoid arthritis (RA) is associated with the increased risk of cardiovascular (CV) mortality and morbidity. There are recommendations by European League against Rheumatism (EULAR) and National Institute for Health and Clinical Excellence (NICE) to include assessment of cardiovascular, osteoporosis, infection and depression risks annually. One of the ways CV..

Published: 19/07/2016
Authors: Patel V, , Abernethy R, Dawson J, Clewes A, Novak J, Cox A, Williams J, O'Rourke T

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Assessing osteoporosis risk

​ Background  Osteoporosis is a major cause of morbidity in patients with RA. It leads to fragility fractures frequently associated with disability, mortality and major financial and social impact. There is no clear guidance regarding when to screen for Osteoporosis in these group of patients who are at high risk compared..

Published: 19/07/2016
Authors: , Patel V, Abernethy R, Dawson J, Clewes A, Novak J, Cox A, Williams J, O'Rourke T

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Self-referral

​ Background:  Nurse Advice Lines have been a long accepted practice in Rheumatology. At St. Helens Hospital we expanded this to a Therapy Advice Line, and noticed an increasing tendency for self referral by our patients. From working parties on management of Early RA and Stable RA we emphasized our self..

Published: 19/07/2016
Authors: Clayton AM, Griffiths AE, Clewes A, Lynch M, Abernethy R, Dawson J

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Acute ortic Valvular Regurgitation

​ Abstract A 40-year-old man with Wegener's granulomatosis with renal and ocular involvement was admitted with symptoms of fever, malaise and cough not responding to oral antibiotics. On initial assessment, he had patchy consolidation but was also found to have a new cardiac murmur. He was mildly anaemic. Within 2 days of..

Published: 19/07/2016
Authors: Clewes A

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St Helens Community Staff

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North West Boroughs Community Health Staff

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