Research Development

Staff Publications

 Small purple icon of a book with a magnifying glass on top  Staff Publications

Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Whitehead IJ'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

The landscape of systemic regimens used routinely in the neoadjuvant setting in the UK

Introduction Neoadjuvant systemic therapy (NST) for breast cancer has potential advantages over adjuvant treatments in selected patient groups. Previous studies identified significant variation in NST utilisation across the UK and a lack of data on routine treatment regimens and real-world outcomes. Aims/Objectives The NeST prospective multi-centre cohort study aimed..

Published: 01/05/2020
Authors: Whitehead IJ

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Surgical outcomes following neoadjuvant chemotherapy

Introduction Potential advantages of neoadjuvant systemic therapy (NST) include downstaging disease to minimise surgery, and in vivo assessment of tumour sensitivity to therapeutic drugs. Considerable variation in NST use remains, however, and it is unclear whether pathological response rates reflect those reported in trials, or whether the downstaging achieved with..

Published: 01/05/2020
Authors: Whitehead IJ

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National utilisation of neoadjuvant systemic therapy and impact on surgical treatment

Introduction Potential advantages of neoadjuvant systemic therapy (NST) include downstaging disease to minimise surgery, and in vivo assessment of tumour sensitivity to therapeutic drugs. Considerable variation in NST use remains, however, and it is unclear whether pathological response rates reflect those reported in trials, or whether downstaging achieved impacts on..

Published: 04/04/2020
Authors: Whitehead IJ

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The NeST (neoadjuvant systemic therapy in breast cancer) study

Introduction Neoadjuvant systemic therapy (NST) has several potential advantages in the treatment of breast cancer. However, there is currently considerable variation in NST use across the UK. The NeST study is a national, prospective, multicentre cohort study that will investigate current patterns of care with respect to NST in the..

Published: 20/01/2020
Authors: Whitehead IJ

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Gynaecomastia: a cosmetic concern or a concerning clinical sign?

Abstract Gynaecomastia is common and often physiological, leading to frequent dismissal as a cosmetic condition. It can however be a symptom of underlying hormone imbalance, which requires further assessment to exclude underlying sinister pathology. We discuss a rare cause of gynaecomastia that demonstrates the importance of a holistic approach to..

Published: 20/12/2019
Authors: Whitehead IJ

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Individualised Expert Feedback is Not Essential

​Objective To determine whether unsupervised video feedback (UVF) is as effective as direct expert feedback (DEF) in improving clinical skills performance for medical students learning basic surgical skills—intravenous cannulation, catheterization, and suturing. Background Feedback is a vital component of the learning process, yet great variation persists in its quality,..

Published: 14/03/2017
Authors: Whitehead IJ

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St Helens Community Staff

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Knowsley Community Staff

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Halton Community Staff

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North West Boroughs Community Health Staff

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