Research Development

Staff Publications

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Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Bonney S'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

The consequences of unnecessary requesting and reporting of the direct antigloblin test in neonates

Background: BSH (British Society of Haematology) guidelines recommend that the Direct Antiglobulin Test (DAT) is only requested when clinically indicated in neonates. Prophylactic anti-D (PAD) administered routinely to Rh D Negative mothers during pregnancy can cause a positive DAT in the neonate that is not clinically relevant as PAD does..

Published: 15/06/2021
Authors: Bonney S, Pannikodu E, Samani S, McNulty J, Chunara U

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BSH2021-PO-115 The effect of an ambulatory care pathway on management of anaemia in a district general hospital

Abstract The burden of iron deficiency anaemia (IDA) is reflected by the rising number of emergency admissions related to IDA and reports of the monumental cost of managing the condition as an inpatient. The National Health Service spends approximately £55 million per annum on IDA-related non-elective admissions, many of which could..

Published: 14/04/2021
Authors: Bonney S

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An audit of the use of prothrombin complex concentration

Background Prothrombin complex concentrate (PCC) is licensed for emergency reversal of anticoagulation in severe and life-threatening bleeding, intracranial haemorrhage and prior to emergency surgery. It is an expensive resource costing approximately Eur2000 per adult dose. There is evidence of inappropriate use of PCC leading to delays to treatment, inappropriate dosing..

Published: 20/02/2019
Authors: Bonney S, Nee PA, Schofield J

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Critical care in the Emergency Department: organ donation

​ Abstract: Organ transplantation is associated with improved outcomes for some patients with end-stage organ failure; however, the number of patients awaiting a transplant exceeds the available organs. Recently, an extended role has been proposed for EDs in the recognition and management of potential donors. The present review presents an illustrative..

Published: 17/02/2017
Authors: Bonney S, Nee PA, Andrews FJ

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Platelet function analysis utilising the PFA-100

​ Introduction Sepsis is known to be associated with impaired platelet function (1). The PFA-100 (Siemens Healthcare, Dade International, Miami, Fla., USA) is a device in which a citrated whole blood sample is aspirated through an aperture coated with agonists inducing platelet activation. Platelet aggregation leads to occlusion of the aperture and..

Published: 16/08/2016
Authors: Bolton N, , Bonney S, Tridente A, Nee PA

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The implementation of a blood conservation strategy

​ I​ntroduction Patients admitted to intensive care units (ICUs) are commonly affected by anaemia, which is contributed to by iatrogenic blood loss from diagnostic testing, with potential risks of increasing transfusion requirements and negative effect on outcomes. Recently published guidelines make several recommendations for the management of anaemia and red..

Published: 19/07/2016
Authors: Tridente A, Bonney S, Nee PA

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Critical Care

​ Abstract Inadequate resuscitation of major haemorrhage is an important cause of avoidable death in severely injured patients. Early recognition of blood loss, control of bleeding and restoration of circulating volume are critical to the management of trauma shock, and transfusion of blood components is a key intervention. Vital signs may..

Published: 19/07/2016
Authors: Bonney S, Mahambrey T, Nee PA

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St Helens Community Staff

Knowsley Community Staff

Halton Community Staff

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North West Boroughs Community Health Staff

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