Research Development

Staff Publications

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Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Green L'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

Is the Current Cut Point for Glycated Haemoglobin (HbA1c) Correct for Diagnosing Diabetes Mellitus in Premenopausal Women? Evidence to Inform Discussion

Abstract Women are on average diagnosed with diabetes mellitus at later age than men but have higher mortality. As the diagnosis of diabetes mellitus is primarily based on HbA1c, the use of a non-specific reference range and cut point for diabetes mellitus that does not account for gender differences..

Published: 30/09/2023
Authors: Green L

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The Effect of the COVID-19 Pandemic on HbA1c Testing

Introduction Studies show that the COVID-19 pandemic disproportionately affected people with diabetes and those from disadvantaged backgrounds. During the first 6 months of the UK lockdown, > 6.6 M glycated haemoglobin (HbA1c) tests were missed. We now report variability in the recovery of HbA1c testing, and its association with diabetes control..

Published: 22/02/2023
Authors: Green L

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Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing

Aims The COVID-19 pandemic, and the focus on mitigating its effects, has disrupted diabetes healthcare services worldwide. We aimed to quantify the effect of the pandemic on diabetes diagnosis/management, using glycated haemoglobin (HbA1c) as surrogate, across six UK centres. Methods Using routinely collected laboratory data, we estimated the..

Published: 17/02/2023
Authors: Green L

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Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time

Aims: We previously showed that the glycated haemoglobin (HbA1c) testing frequency links to diabetes control. Here, we examine the effect of variability in test interval, adjusted for the frequency, on change in HbA1c (ΔHbA1c). Materials & Methods: HbA1c results were collected on 83,872 people with HbA1c results..

Published: 16/05/2022
Authors: Green L

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P98 Variability in test interval is linked to glycated haemoglobin (HbA1c) trajectory over time in people with diabetes

Introduction Frequency of HbA1c testing links to outcome in terms of HbA1c control in diabetes. The influence of the variability of test-retest interval on HbA1c change needs to be determined. Methods HbA1c results were collected from laboratory records on 3,872 people: HbA1c results at baseline and 5..

Published: 23/03/2022
Authors: Green L

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Can we check serum lithium levels less often without compromising patient safety?

Background Lithium is viewed as the first-line long-term treatment for prevention of relapse in people with bipolar disorder. Aims This study examined factors associated with the likelihood of maintaining serum lithium levels within the recommended range and explored whether the monitoring interval could be extended in some cases. Method We..

Published: 17/12/2021
Authors: Green L

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Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis

Aims The COVID-19 pandemic, and the focus on mitigating its effects, has disrupted diabetes healthcare services worldwide. We aimed to quantify the effect of the pandemic on diabetes diagnosis/management, using glycated haemoglobin (HbA1c) as surrogate, across six UK centres. Methods Using routinely collected laboratory data, we estimated the..

Published: 13/10/2021
Authors: Green L

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Impact of the UK COVID‐19 pandemic on HbA1c testing and its implications for diabetes diagnosis and management

Extract Letter to the Editor Diabetes mellitus (DM) is a risk factor for poor outcome in patients with COVID‐19.1 However, the focus on mitigating the effects of SARS‐CoV‐2 has resulted in many routine healthcare services, including blood test monitoring in conditions such as DM, being disrupted. We recently explored..

Published: 19/03/2021
Authors: Green L

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Serum lithium test requesting across three UK regions: an evaluation of adherence to monitoring guidelines

Background Bipolar disorder is the fourth most common mental health condition, affecting ~ 1% of UK adults. Lithium is an effective treatment for prevention of relapse and hospital admission, and is widely recommended as a first-line treatment. We previously showed in other areas that laboratory testing patterns are variable with sub-optimal conformity..

Published: 12/01/2021
Authors: Green L

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