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Research Development

Staff Publications

 Small purple icon of a book with a magnifying glass on top  Staff Publications

Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Pritchard-Jones R'


Mersey and West Lancashire Teaching Hospitals Staff

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St Helens and Knowsley Hospital Staff - Publications pre April 2024

Leg Lymphoedema After Inguinal and Ilio-Inguinal Lymphadenectomy for Melanoma: Results from a Prospective, Randomised Trial

Background The Evaluation of Groin Lymphadenectomy Extent for Melanoma (EAGLE FM) study sought to address the question of whether to perform inguinal (IL) or ilio-inguinal lymphadenectomy (I-IL) for patients with inguinal nodal metastatic melanoma who have no clinical or imaging evidence of pelvic disease. Primary outcome measure was disease-free survival..

Published: 17/03/2024
Authors: Pritchard-Jones R

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Accuracy of PET/CT in the diagnosis of pelvic lymph node metastases in melanoma: A subgroup analysis of the evaluation of groin lymphadenectomy extent for metastatic melanoma (EAGLE-FM) trial

Background PET/CT is widely used in the staging of patients with melanoma groin lymph node (LN) metastases. This study aims to utilise prospectively collected data to determine the accuracy of this modality in the diagnosis of pelvic metastases in those patients with known inguinal LN involvement.   Russell, M; Pritchard-Jones,..

Published: 14/02/2024
Authors: Pritchard-Jones R

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Accuracy of a tool to prioritise patients awaiting elective surgery: an implementation report

Study objective The objective of this study was to evaluate the accuracy of a new elective surgery clinical decision support system, the ‘Patient Tacking List’ (PTL) tool (C2-Ai(c)) through receiver operating characteristic (ROC) analysis. Methods We constructed ROC curves based on risk predictions produced by the tool and..

Published: 20/01/2023
Authors: Pritchard-Jones R

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P-135 First experience with a new closed incision negative pressure wound therapy, Prevena TM

Aim Surgical site infection (SSI) contributes a significant proportion of post operative morbidity in patients undergoing abdominal wall reconstruction (AWR). PrevenaTM closed incision negative pressure wound therapy (ciNPT) has been demonstrated to reduce SSI rates in the elective and emergency laparotomy setting. However, there is no evidence for PrevenaTM use..

Published: 13/10/2022
Authors: Dixon S, Benson A, Kalaiselvan R, Kanwar S, Samad A, Pritchard-Jones R, West C, Scott M

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OC-022 Maintaining an elective abdominal wall reconstruction service during the COVID 19 pandemic

Aim Elective surgery services suffered significantly due to the COVID-19 pandemic. The aim of this study was to analyse the impact and outcomes of abdominal wall reconstruction (AWR) performed during the COVID-19 pandemic, assessing safety and sustainability. Material & Methods A retrospective review of all patients undergoing AWR in a single..

Published: 10/10/2022
Authors: Dixon S, Benson A, Kalaiselvan R, Kanwar S, Samad A, Pritchard-Jones R, West C, Scott M

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Electrochemotherapy for the treatment of cutaneous squamous cell carcinoma: The INSPECT experience (2008-2020)

Introduction Cutaneous squamous cell carcinoma (cSCC) is a frequent skin cancer with a high risk of recurrence characterized by tumor infiltration and, in advanced cases, a poor prognosis. ECT (electrochemotherapy) is an alternative treatment option for locally advanced or recurrent cSCC that is unsuitable for surgical resection. In this study,..

Published: 20/09/2022
Authors: Pritchard-Jones R

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National audit of non-melanoma skin cancer excisions performed by plastic surgery in the UK

Introduction Keratinocyte or non-melanoma skin cancer (NMSC) is the most common malignancy worldwide, encompassing basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC). The mainstay of treatment for NMSC is excision. The likelihood of recurrence is directly related to achieving tumour-free margins. Just 1 per cent of BCCs recur where..

Published: 27/07/2022
Authors: Nolan G, Pritchard-Jones R

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Clinical Outcomes and Risk Stratification of Early-Stage Melanoma Micrometastases From an International Multicenter Study

Purpose Indications for offering adjuvant systemic therapy for patients with early-stage melanomas with low disease burden sentinel node (SN) micrometastases, namely, American Joint Committee on Cancer (AJCC; eighth edition) stage IIIA disease, are presently controversial. The current study sought to identify high-risk SN-positive AJCC stage IIIA patients who are more..

Published: 18/07/2022
Authors: Nolan G, Pritchard-Jones R

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Evaluation of the Indications for Sentinel Node Biopsy in Early-Stage Melanoma with the Advent of Adjuvant Systemic Therapy

Background Patients presenting with early-stage melanoma (AJCC pT1b-pT2a) reportedly have a relatively low risk of a positive SNB (~5–10%). Those patients are usually found to have low-volume metastatic disease after SNB, typically reclassified to AJCC stage IIIA, with an excellent prognosis of ~90% 5-year survival. Currently, adjuvant systemic therapy is..

Published: 13/05/2022
Authors: Nolan G, Pritchard-Jones R

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Combination of Pembrolizumab with Electrochemotherapy in Cutaneous Metastases from Melanoma

Simple Summary Electrochemotherapy (ECT) combines a cytotoxic agent with locally applied electric pulses to enhance its antitumor effect. Over the last 15 years, ECT has been safely applied to patients with skin metastases in combination with other oncologic treatments and, more recently, with systemic immunotherapy. In this study, we aimed to..

Published: 25/08/2021
Authors: Pritchard-Jones R

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The effect of the COVID‐19 pandemic on skin cancer surgery in the United Kingdom: a national, multi‐centre, prospective cohort study and survey of Plastic Surgeons

Editor The COVID‐19 pandemic has negatively affected all skin cancer treatment. A national audit of skin cancer excisions by Plastic Surgeons was adapted to establish what effect the pandemic had on the provision and delivery of skin cancer treatment in the United Kingdom. Throughout ‘lockdown’ (March 16th – June 14th 2020) a..

Published: 01/11/2020
Authors: Nolan G, Pritchard-Jones R

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Electrochemotherapy in the treatment of cutaneous malignancy

Background Electrochemotherapy (ECT) is a treatment for both primary and secondary cutaneous tumours. The international Network for sharing practices on ECT group investigates treatment outcomes after ECT using a common database with defined parameters. Methods Twenty-eight centres across Europe prospectively uploaded data over an 11-year period. Response rates were investigated..

Published: 21/10/2020
Authors: Pritchard-Jones R

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Skin cancer surgery during the COVID-19 pandemic: A national, multicentre, prospective cohort study and survey of plastic surgeons

Abstract Skin cancer is the most common malignancy worldwide. The COVID‐19 pandemic has caused an unprecedented reorganization of healthcare services. This study established what effect the pandemic has had on the provision of skin cancer surgery by plastic surgeons in the U.K., one of the worst affected countries globally...

Published: 01/09/2020
Authors: Nolan G, Pritchard-Jones R

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Discretionary technology bootlegging tensions in institutional healthcare work

Abstract We explore individuals who take some of their technology use ‘underground’, described as ‘bootlegging’, to enhance healthcare work. We find that healthcare professionals’ informal use of mobile applications in healthcare work sometimes ‘sticks out’ and this produces professional identity tensions: (1) conflict with perceptions of professional behaviour, and (2) defilement of..

Published: 08/06/2020
Authors: Pritchard-Jones R

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Understanding technology mediation and new service provider roles in health care

Purpose Service research holds that as services become more technology dominated, new service provider roles emerge. On a conceptual level, the potential impact of different roles has been discussed with regard to service provider readiness, job performance and overall experience. However, as yet, there is sparse empirical support for these..

Published: 08/06/2020
Authors: Pritchard-Jones R

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Current role of sentinel lymph node biopsy in the management of cutaneous melanoma

Summary Sentinel node biopsy (SNB) has been at the forefront of the surgical staging of melanoma patients for the past 15 years. The high accuracy of this prognostic staging procedure is now recognised in all international guidelines for melanoma. However during this period there have been a number of important changes..

Published: 08/06/2020
Authors: Pritchard-Jones R

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Electrochemotherapy in the treatment of metastatic malignant melanoma: A prospective cohort study by InspECT

​ Background Electrochemotherapy (ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour. The aim of this study was to investigate the effectiveness of ECT in cutaneous metastases of melanoma and to identify factors which affect (..

Published: 14/03/2017
Authors: Pritchard-Jones R, Liew S

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P054: Electrochemotherapy in the treatment

Aims  Electrochemotherapy (ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour. The aim of this study was to investigate the effectiveness of ECT in cutaneous metastases of melanoma and to identify factors which affect (..

Published: 21/02/2017
Authors: Liew S, Pritchard-Jones R

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The Mersey Burns App

​ Introduction  ‘Mersey Burns App’ is a smartphone/tablet application that aids in the assessment of total burn surface area (TBSA) and calculation of fluid resuscitation protocols in burns. This paper presents two studies assessing the speed and accuracy of calculations using Mersey Burns (App) in comparison with a Lund and..

Published: 19/07/2016
Authors: Barnes J, Pritchard-Jones R, McArthur P, Shokrollahi K,

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Southport and Ormskirk Hospital Staff - Publications pre April 2024

St Helens Primary and Community Staff

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Knowsley Primary and Community Staff

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Halton Primary and Community Staff

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North West Boroughs Community Health Staff

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