Research Development

Staff Publications

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Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Malhotra P'



Mersey and West Lancashire Teaching Hospitals NHS Trust – St Helens & Knowsley Staff

Impact of the coronavirus pandemic and national lockdown on a lung cancer service – opportunities for innovation

Background Timely diagnosis and access to treatment are key factors in improving outcomes in lung cancer. The emergence of the coronavirus pandemic posed unprecedented challenges, with impacts felt across the entire care pathway from presentation to diagnosis and access to treatment. Objective(s): To compare referrals and outcomes for key..

Published: 16/06/2021
Authors: Malhotra P, McIntosh A, Peers V

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Corticosteroids reduce mortality and prevent ICU admission in Covid-19 pneumonia

Abstract Can early use of corticosteroids prevent progression of Covid-19 pneumonia to full-blown ARDS, and reduce mortality? Clinical data for use of corticosteroids in severe coronavirus infections are mixed - there is a particular lack of evidence in patients in the pre-critical care stage of illness i.e. before decompensation..

Published: 16/09/2020
Authors: Heaton J, Malhotra P, Stockton P, Rossiter L

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Lung cancer stage-shift following a symptom awareness campaign

Background  Lung cancer outcomes in the UK are worse than in many other developed nations. Symptom awareness campaigns aim to diagnose patients at an earlier stage to improve cancer outcomes.   Methods  An early diagnosis campaign for lung cancer commenced in Leeds, UK in 2011 comprising public and primary-care facing components. Rates..

Published: 24/07/2018
Authors: Malhotra P

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British Thoracic Society quality standards for the investigation and management of pulmonary nodules

Introduction  The purpose of the quality standards document is to provide healthcare professionals, commissioners, service providers and patients with a guide to standards of care that should be met for the investigation and management of pulmonary nodules in the UK, together with measurable markers of good practice. Methods  Development of..

Published: 18/05/2018
Authors: Malhotra P

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Straight to CT delivers earlier first definitive treatment

Background  The National Optimal Lung Cancer Pathway (NOLCP) recommends performing a CT scan before a patients first appointment in a rapid access suspected lung cancer clinic. A local audit in 2014 at our hospital which receives over 350 two week rule suspected lung cancer referrals per year found that less than 50% of..

Published: 16/05/2017
Authors: Malhotra P, Murphy P, Dawson C, Hunt N, Hendry J

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Assessing the diagnostic accuracy

​ Background  The British Thoracic Society guidelines (2015) on the investigation and management of pulmonary nodules recommend the use of two risk prediction tools to assess the likelihood of malignancy in solid pulmonary nodules (Brock model following initial CT and the model described by Herder et al. following PET-CT). Management strategies are..

Published: 19/07/2016
Authors: Malhotra P

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P244 The impact of “Seven Day working”

​ Abstract St Helens and Knowsley NHS trust (STHK) have re designed the acute pathway for medical admissions. Investment in Consultant numbers has allowed the Acute Medical Admissions (MAU) team and the speciality teams to provide robust Consultant input to their areas Monday to Sunday. Speciality Consultants have been released from..

Published: 19/07/2016
Authors: Twite S, Stockton P, Malhotra P

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Risk of malignancy in pulmonary nodules

​ Objectives Clinical prediction models assess the likelihood of malignancy in pulmonary nodules detected by computed tomography (CT). This study aimed to validate four such models in a UK population of patients with pulmonary nodules. Three models used clinical and CT characteristics to predict risk (Mayo Clinic, Veterans Association, Brock University)..

Published: 19/07/2016
Authors: Malhotra P

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Investigation and management of pulmonary nodules

​ SUMMARY OF RECOMMENDATIONS This guideline is based on a comprehensive review of the literature on pulmonary nodules and expert opinion. Although the management pathway for the majority of nodules detected is straightforward it is sometimes more complex and this is helped by the inclusion of detailed and specific recommendations and..

Published: 19/07/2016
Authors: Malhotra P

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Positron emission tomography

​ Introduction  Positron Emission Tomography (PET) is an important tool in the evaluation of pulmonary nodules. A number of risk prediction tools attempt to discriminate between benign and malignant nodules. Herder et al previously demonstrated an improvement in performance of the Mayo risk prediction tool when information regarding FDG avidity was..

Published: 19/07/2016
Authors: Malhotra P

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Haemoptysis with a normal chest X ray

​ Introduction Haemoptysis is a red-flag symptom for lung cancer, but there is no consensus on how to investigate patients with haemoptysis and a normal chest X-ray. We sought to determine the yield of CT and bronchoscopy in this patient population in patients attending two hospitals in Northern England. Methods Patients..

Published: 19/07/2016
Authors: Malhotra P

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Dedicated pneumonia follow up clinic

​ Background  It is routine clinical practice, based on British Thoracic Society recommendations, to arrange a clinical review and chest x-ray approximately 6 weeks following an episode of pneumonia in most patients. However there is a paucity of published evidence to support or refute this practice. Objective  To determine the clinical and..

Published: 19/07/2016
Authors: Komrower D, Malhotra P, Shanker V, Stockton P, Twite S

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St Helens Community Staff

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Knowsley Community Staff

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Halton Community Staff

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North West Boroughs Community Health Staff

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