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Research Development

Staff Publications

 Small purple icon of a book with a magnifying glass on top  Staff Publications

Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.

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All publications by 'Liew S'


Mersey and West Lancashire Teaching Hospitals Staff

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St Helens and Knowsley Hospital Staff - Publications pre April 2024

Electrochemotherapy in the treatment of ulcerated malignant tumors: Results from the inspect registry

Background Electrochemotherapy (ECT) is an effective local treatment for cutaneous tumors and metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour. The aim of this study was to investigate the effectiveness of ECT in ulcerated versus non-ulcerated cutaneous tumors and metastases. Methods 22..

Published: 15/04/2020
Authors: Liew S

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0162 Outcomes of surgery following chemoradiotherapy for anal cancer: A 10-year retrospective study

Aim Anal cancer accounts for less than 1% of all cancers but carries considerable morbidity and mortality. We reviewed clinicopathological outcomes for patients undergoing surgery following chemoradiotherapy (CRT) for anal cancer. Method(s) A retrospective review of casenotes from patients undergoing surgery for anal cancer from 2008 -2018 was performed. Patients were..

Published: 01/09/2019
Authors: Liew S

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Basal cell carcinoma and electrochemotherapy

Background Basal cell carcinoma(BCC) is one of the most common skin malignancies worldwide. In comparison to current management strategies for BCC, electrochemotherapy (ECT) proved to be a valid alternative in the management of primary and secondary lesions. ECT refers to intratumoural or intravenous injection of bleomycin followed by the..

Published: 12/03/2019
Authors: Liew S

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Electrochemotherapy as an adjunct to the surgical management of metastatic melanoma

Background Electrochemotherapy is a treatment for tumours in the skin, both primary and metastatic. The international Network for sharing practices on Electrochemotherapy (InspECT) group gathers information on treatment outcomes in a common database with defined, outcome parameters in order to improve and guide the use of Electrochemotherapy (ECT). Over a..

Published: 12/03/2019
Authors: Liew S

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Single centre outcomes of surgery following chemoradiotherapy for anal cancer

​Aim Anal cancer accounts for less than 1% of all cancers but carries considerable morbidity and mortality. We reviewed clinicopathological outcomes for patients undergoing surgery following chemoradiotherapy (CRT) for anal cancer. Methods A retrospective review of casenotes from patients undergoing surgery for anal cancer from 2008-2017 was performed. Patients were identified..

Published: 14/08/2018
Authors: Liew S

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Electrochemotherapy for Breast Cancer—Results From the INSPECT Database

Background Cutaneous recurrence from breast cancer can pose a clinical challenge. It might be the only disease site, or could be part of disseminated disease, and often profoundly affects quality of life. Electrochemotherapy is a palliative treatment using electric pulses to locally permeabilize tumor cells and thereby significantly increase bleomycin..

Published: 16/05/2018
Authors: Liew S

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Electrochemotherapy of unresectable cutaneous tumors with reduced dosages of intravenous bleomycin: analysis of 57 patients from the InspECT (International network for sharing practices of ElectroChemoTherapy) registry

​ Abstract BACKGROUND: Electrochemotherapy (ECT) is currently used to treat unresectable superficial tumors of different histotypes through the combination of cytotoxic chemotherapy and local application of electric pulses. In 2006, a collaborative project defined the ESOPE (European Standard Operating Procedures of Electrochemotherapy) guidelines to standardize the procedure. The International Network for Sharing..

Published: 20/12/2017
Authors: Liew S

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FC1.9 Prospective pilot study evaluating the effectiveness of electrochemotherapy

​ Background Electrochemotherapy (ECT) is currently used to treat cutaneous and subcutaneous tumors of different histotypes. ECT combines cytotoxic drugs and the application of high-intensity electric pulses to increase cell permeability. In 2006, a multicenter European project (ESOPE, European Standard Operating Procedures of Electrochemotherapy) defined the guidelines for ECT application. To date,..

Published: 16/08/2017
Authors: Liew S

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Electrochemotherapy in the treatment of metastatic malignant melanoma: A prospective cohort study by InspECT

​ Background Electrochemotherapy (ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour. The aim of this study was to investigate the effectiveness of ECT in cutaneous metastases of melanoma and to identify factors which affect (..

Published: 14/03/2017
Authors: Pritchard-Jones R, Liew S

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P054: Electrochemotherapy in the treatment

Aims  Electrochemotherapy (ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour. The aim of this study was to investigate the effectiveness of ECT in cutaneous metastases of melanoma and to identify factors which affect (..

Published: 21/02/2017
Authors: Liew S, Pritchard-Jones R

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Ulcerating metastatic inguinal lymphadenopathy

​ Sadri, A; Touil, L; Liew, SW; Brackley, P; Koshy, O. (2014).  Salvage of ulcerating metastatic inguinal lymphadenopathy using the inferior pedicled TRAM flap . Journal of Plastic, Reconstructive & Aesthetic Surgery. 67 (5), E138-9  

Published: 19/07/2016
Authors: Touil L, Liew S, Brackley P, Koshy O

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Nodal recurrence of cutaneous malignant melanoma

​ Summary We report the case of an 84-year-old woman who had a nodal recurrence of melanoma 45 years after the primary diagnosis of an extremity cutaneous melanoma. It is believed to be the longest disease-free latency period reported between primary melanoma diagnosis and recurrence to date. Late recurrences of melanoma are..

Published: 19/07/2016
Authors: Liew S

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Salvage Anal Cancer Surgery (SACS)

​ Introduction:  2004 NICE guidance on anal carcinomas advised treatment by specific multidisciplinary teams (MDTs). The National Peer Review Programme recommended each cancer network have a single anal carcinoma MDT and single salvage surgery centre. We present the results of this service. Methods:  A retrospective case note audit was performed of all..

Published: 19/07/2016
Authors: Liew S

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St Helens Community Staff

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Knowsley Community Staff

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Halton Community Staff

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North West Boroughs Community Health Staff

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