Research Development
Staff Publications
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Staff Publications
Research Development
Find out what your colleagues have been writing. This section features articles published by staff working for St Helens and Knowsley Teaching Hospitals and Halton, Knowsley and St Helens community staff.
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Introduction Lobular carcinomas account for around 10% of invasive breast cancers. Accuracy of pre-operative evaluation can be troublesome. NICE guidelines recommend MRI "to assess the tumour size if breast-conserving surgery is being considered for invasive lobular cancer". However, each additional investigation introduces cost and potentially prolongs the treatment pathway, which is..
Published: | 02/05/2022 |
Authors: | Wadsworth P, Rimmer L, Sepesiova L, Fong J, Kiernan T, Harris O |
Introduction Impalpable breast cancers can be localised using different techniques. Recently, magnetic seed localisation systems have been developed and shown to offer benefits over traditional wire guided techniques. This study aims to assess the feasibility of a new seed localisation device, Sirius Pintuition, at St Helen's and Knowsley NHS Trust. ..
Published: | 02/05/2022 |
Authors: | Foster R, Bathla S, Harris O, Jois RHS, Kiernan T, Ray A, Chagla LS |
Background Breast augmentation is the most commonly performed cosmetic procedure, and increasingly women in this group present with breast cancer or request risk-reducing surgery, but their optimal management is unclear. The authors explored the clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation and compared..
Published: | 09/02/2022 |
Authors: | Kiernan T, Clifford R, Chagla LS, Iqbal A |
Background Breast augmentation is the most commonly performed cosmetic procedure, and increasingly women in this group present with breast cancer or request risk-reducing surgery, but their optimal management is unclear. The authors explored the clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation and compared..
Published: | 01/02/2022 |
Authors: | Kiernan T, Clifford R, Chagla LS, Iqbal A |
Background: We present a case report of a 45 year old female who presented with bilateral breast masses and one of these was shown to be a rare primary breast tumour. Malignant adenomyoepithelioma (AME-M) exhibits a classic biphasic proliferation of epithelial and myoepithelial cells, either or both of which have undergone..
Published: | 08/09/2021 |
Authors: | Stevenson J, Kiernan T, McKeown D, Innes H, Shaw M |
Background Screening and the use of Neoadjuvant therapy has increased the number of breast lesions requiring localisation. The search for the ideal technique is still on. ROLL (Radioisotope guided Occult Lesion Localisation) is a reliable technique though not widely available, Magnetic Seed, is a new alternative. These two techniques have..
Published: | 01/05/2021 |
Authors: | Jois RHS, Pushdary KH, Patnam V, Gupta N, Kiernan T, Bathla S, Ray A, Harris O, Chagla LS |
Summary Primary melanoma of the breast parenchyma (PMPB) is a rare and aggressive disease, with only a few cases reported in the literature. We present the case of a 50-year old woman who underwent mastectomy and immediate breast reconstruction using a free DIEP flap following recurrence after breast conserving surgery...
Published: | 18/12/2020 |
Authors: | Snashall E, Kiernan T, Harper-Machin A, Taghizadeh R |
Purpose The 21-gene recurrence score (Oncotype DX) (RS) informs systemic therapy decision making in ER-positive HER2-negative early breast cancer (BC). To date no study has described the more nuanced discussions that take place regarding systemic therapy or the impact of the RS on concordance in such decision making. Here..
Published: | 20/02/2019 |
Authors: | Kiernan T |
Introduction Mastectomy closure without drains has many potential advantages. This study compares a lysine-based high strength adhesive with standard wound drain application. Methods An ethically approved post-market non-inferiority multicentre randomized trial compared standard closure with drains (SWC) vs drain-free closure with adhesive (DFTG) in mastectomy +/-SLNB. Primary outcome was the..
Published: | 15/08/2018 |
Authors: | Kiernan T |
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